Drug-induced leukocytoclastic vasculitis: tigecycline a rare cause

  • Kalpana Bhairavarasu a faculty member in Rheumatology at Texas Tech University Health Sciences Center in Odessa, TX.
  • Satish Mocherla a clinical assistant professor in Infectious Disease at TTUHSC in Odessa, TX.
  • Jaya Amaram a resident in Internal Medicine at TTUHSC in Odessa, TX.
  • Ena Sharma a resident in Internal Medicine at TTUHSC in Odessa, TX.
  • Philip A Conlin a pathologist at DX Laboratories in Midland, TX.
  • Imran Umer a resident in Internal Medicine at TTUHSC in Odessa, TX.
Keywords: Drug-induced vasculitis, leukocytoclastic vasculitis, tigecycline-induced vasculitis, tigecycline related leukocytoclastic vasculitis

Abstract

Drug-induced leukocytoclastic vasculitis is an inflammation of blood vessels triggered by various drugs. It presents with a localized skin rash but may involve the internal organ systems, including the gastrointestinal tract, kidneys, lungs, central nervous system, and joints. The clinical recognition of drug-induced vasculitis is very important because continued use of the culprit drug can be organ or life threatening. The prognosis is excellent if the disease is limited to the skin and diagnosed promptly. The use of tigecycline has recently increased due to resistance patterns of bacteria, and it is important to recognize this potential adverse effect of this drug and to diagnose and treat the patient early to achieve a favorable outcome. To best of our knowledge, we report the first case of tigecycline-induced leukocytoclastic vasculitis.

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Published
2015-01-08
How to Cite
Bhairavarasu, K., Mocherla, S., Amaram, J., Sharma, E., Conlin, P. A., & Umer, I. (2015). Drug-induced leukocytoclastic vasculitis: tigecycline a rare cause. The Southwest Respiratory and Critical Care Chronicles, 3(9), 55-58. Retrieved from https://pulmonarychronicles.com/index.php/pulmonarychronicles/article/view/184