Updates on management of advanced heart failure
Abstract
Advanced heart failure defines a subset of patients with heart failure with reduced ejection
fraction having severe symptoms despite usual recommended therapy. These patients require
frequent hospitalizations and specialized interventions, such as cardiac transplantation,
implantation of mechanical circulatory support devices, continuous intravenous inotropic
therapy to palliate symptoms, or continued terminal care. This review summarizes the
management of advanced heart failure with updates in medical therapy and recent advances
in surgical therapy, particularly left ventricular assist device therapy.