Exercise-induced exertional rhabdomyolysis
Abstract
Rhabdomyolysis is a condition resulting from skeletal muscle breakdown that can present in several ways, ranging from no symptoms to a life threatening renal disorder. A variety of insults, including trauma, toxins, drugs, infections, and exercise, can lead to muscle breakdown. Complications include compartment syndrome, electrolyte imbalance, and cardiac arrest. Rhabdomyolysis is a clinical challenge due to the range of its presentations. We report a 22-year-old male college student who came to the emergency department with mild thigh soreness and dark urine. A full work-up showed his serum creatine kinase was significantly elevated to 178,786 U/L and he had acute kidney injury. Our patient had no toxin or drug exposure, no infection, no trauma, and no crush injuries, but he had attended a 45-minute spinning class several days prior to admission, indicating a case of exercise-induced exertional rhabdomyolysis. He was hospitalized and treated with IV hydration to protect his kidneys. After eight days of conservative treatment with IV fluids, the patient’s creatine kinase level normalized. This case illustrates that even patients with minimal risk factors for rhabdomyolysis can present with severe kidney injury requiring prolonged hospitalization.Downloads
References
Kim J, Lee J, Kim S, et al. Exercise-induced rhabdomyolysis
mechanisms and prevention: A literature review. J Sport
Health Science 2016; 5(3):324–33.
Defilippis EM, Kleiman DA, Derman PB, et al. Spinninginduced
rhabdomyolysis and the risk of compartment
syndrome and acute kidney injury. Sports Health: A Multidisciplinary
Approach 2014; 6(4):333–5.
Petejova N, Martinek A. Acute kidney injury due to rhabdomyolysis
and renal replacement therapy: a critical review.
Critical Care 2014; 18(3):224.
Kim D, Ko E-J, Cho H, et al. Spinning-induced rhabdomyolysis:
eleven case reports and review of the literature. Electrolytes
and Blood Pressure 2015; 13(2):58.
Ramme AJ, Vira S, Alaia MJ, et al. Exertional rhabdomyolysis
after spinning: case series and review of the literature.
J Sports Med Phys Fitness 2016; 56(6):789–793.
Brogan M, Ledesma R, Coffino A, et al. Freebie rhabdomyolysis:
a public health concern. spin class-induced rhabdomyolysis.
The American J Medicine 2017; 130(4):484–7.
Krivickas LS. Recurrent rhabdomyolysis in a collegiate
athlete. Medicine & Science in Sports & Exercise 2006;
(3):407–10.
Hannah-Shmouni F, Mcleod K, Sirrs S. Recurrent exerciseinduced
rhabdomyolysis. Canadian Medical Association J
184(4):426–30.
Gilliam S. Sickle Cell Trait, Rhabdomyolysis, and mortality
among U.S. Army soldiers. The J Emergency Medicine
; 51(5):616.
Atias D, Druyan A, Heled Y. Recurrent exertional rhabdomyolysis.
Current Sports Medicine Reports 2013;
(6):365–9.
Bagley WH, Yang H, Shah KH. Rhabdomyolysis. Internal
and Emergency Medicine. 2007; 2(3):210–8.
Brown CVR, Rhee P, Chan L, et al. Preventing renal failure
in patients with rhabdomyolysis: do bicarbonate and mannitol
make a difference? The J Trauma: Injury, Infection, and
Critical Care 2004; 56(6):1191–6.
Zeng X, Fu P. Continuous renal replacement therapy
(CRRT) for rhabdomyolysis. Cochrane Database of Systematic
Reviews 2014; 6:CD008566.
Better O, Stein JH. Early management of shock and prophylaxis
of acute renal failure in traumatic rhabdomyolysis.
N Engl J Med 1990; 322:825–9.