Cesar Peralta MD, Bhavana Yalamanchili MBBS, Andres Yepes, MD
We present the case of a 75-year-old female with a history of ductal carcinoma in situ (DCIS) of the right breast who later developed complications suggestive of metastatic disease. Through a coordinated multidisciplinary effort involving imaging, thoracentesis, pleuroscopy, and cryobiopsy, a diagnosis of metastatic adenocarcinoma was established. This case highlights the diagnostic importance of minimally invasive thoracic procedures in patients with suspected metastatic disease.
Keywords: Breast cancer, metastatic adenocarcinoma, pleuroscopy, cryobiopsy, pleural effusion, pulmonary nodules, double lumen intubation, Heimlich valve
Article citation: Peralta C, Yalamanchili B, Yepes A. Metastatic breast cancer presenting with pleural effusion and pulmonary nodules: A multimodal diagnostic approach. The Southwest Journal of Medicine 2025;13(57):69–71
From: Texas Tech University Health Sciences Center School of Medicine, Lubbock, Texas (MM) Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas (CP, BY, AY)
Submitted: 9/3/2025
Accepted: 9/25/2025
Conflicts of interest: none
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