Esophageal actinomycosis – a rare cause of odynophagia in an HIV patient

  • Ben Thiravetyan Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas https://orcid.org/0000-0002-3212-912X
  • Tulaton Sodsri Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USA https://orcid.org/0000-0002-8999-5133
  • Chanokporn Puchongmart Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USA https://orcid.org/0000-0001-7504-214X
  • Jacob Nichols Division of Infectious Diseases, Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USA

Abstract

Odynophagia is a common complaint among individuals living with HIV, with candidiasis
being the predominant cause. We present a case of 38-year-old man with poorly controlled HIV
who presented with odynophagia and oropharyngeal candidiasis that is refractory to antifungal
therapy. Further investigations showed esophageal candidiasis with esophageal ulcers, which
pathology revealed extensive filamentous bacteria in addition to fungal hyphae. Diagnosis of
esophageal candidiasis superimposed with actinomycosis was made, and he responded well
to amoxicillin in addition to fluconazole therapy.
Keywords: Esophageal actinomycosis, Actinomycosis, Actinomyces, HIV

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Published
2025-10-23