Sugammadex: A neuromuscular blockade agent encapsulator

Victoria Yepes Hurtado BSN, RN

ABSTRACT

Sugammadex sodium, a modified γ-cyclodextrin, represents a new class of drugs effective at reversing non-depolarizing muscle relaxants rocuronium and vecuronium. The cylindrical, basket-like structure encapsulates neuromuscular blocking agents which results in rapid reversal of paralysis within three minutes. The current literature was reviewed to analyze the clinical implications and considerations with its administration.

Keywords: cyclodextrin, encapsulation, selective relaxant binding agent, sugammadex, supramolecular


Article citation: Yepes Hurtado V. Sugammadex: a neuromuscular blockade agent encapsulator. The Southwest Respiratory and Critical Care Chronicles 2017;5(20):44-49.
From: University Medical Center, Lubbock, TX.
Submitted: 4/30/2017
Accepted: 7/4/2017
Reviewer: John Wasnick MD
Conflicts of interest: none