Recurrences of giant cell tumor of bone within soft tissue

Dylan Homen MD, George Brindley MD, Cody Beaver MD


Giant cell tumor of bone (GCTB) is typically considered an aggressive but benign tumor, and recurrence of the tumor following surgical intervention is common. It is much rarer, however, for recurrence to occur in the soft tissue surrounding the original lesion. Literature investigating recurrent giant cell tumor of soft tissue is much more limited than literature on bony recurrence, and our understanding of its etiology is still developing. This report reviews two cases in which recurrence of the tumor occurred in the adjacent soft tissue following intralesional excision of GCTB; our aim is to identify variables that could have contributed to this atypical recurrence and to stimulate more investigations into methods for possible prevention.

Keywords: giant cell tumor, bone, soft tissue, recurrence

Article citation: Homen D, Brindley G, Beaver C. Recurrences of giant cell tumor of bone within soft tissue. The Southwest Respiratory and Critical Care Chronicles 2020;8(34):56–60
From: Department of Orthopedics, Texas Tech University Health Sciences Center, Lubbock, Texas
Submitted: 2/23/2020
Accepted: 4/15/2020
Reviewer: Chok Limsuwat MD
Conflicts of interest: none
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