Ashish Sarangi MD, Lance Mwangi BA, E.L. Domingo-Johnson BSN, Arham Siddiqui BA
Background: Anticholinergics are one of the first-line treatments for patients with dystonia. However, there are few practical guidelines for patients with dystonia who have developed hypersensitivity to anticholinergics.
Methods and Findings: This update was developed to provide clinicians with specific alternatives if patients are hypersensitive to anticholinergics but require management of dystonia. Recommendations were based upon literature review and expert opinion.
Conclusions: We provide the guidance on patients with dystonia who are hypersensitive to anticholinergics, based on a review of the literature. We propose personalized dystonia treatment approaches when anticholinergic hypersensitivity arises. Gaps in the existing literature and future directions in the treatment of anticholinergic hypersensitive patients being treated for dystonia are also highlighted.
Keywords: Dystonia, anticholinergics, hypersensitivity, antihistamine, cognitive behavior
Article citation: Sarangi A, Lance Mwangi L, Domingo-Johnson EL, Siddiqui A. Management of dystonia in patients with hypersensitivity to anticholinergics. The Southwest Respiratory and Critical Care Chronicles 2021;9(39):35–40
From: Department of Psychiatry, Texas Tech University Health Sciences Center, Lubbock, Texas
Submitted: 10/3/2020
Accepted: 4/3/2021
Reviewer: Kenneth Nugent MD
Conflicts of interest: none
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