Uremic pericarditis: a case report of favorable outcomes with early detection and management

Abstract

Uremic pericarditis is a rare, potentially life-threatening complication of end-stage renal disease (ESRD) caused by the accumulation of uremic toxins. This case report describes a 32-year-old man with diabetes and ESRD on hemodialysis who developed uremic pericarditis. The patient presented with fever, chest pain, dyspnea, cough, and foot pain. Diagnostic investigations led to treatment with broad-spectrum antibiotics and surgical debridement of a necrotizing soft tissue infection of the right foot. The lack of clinical improvement in hemodynamic status prompted rapid investigation with electrocardiography and echocardiography, confirming the diagnosis of uremic pericarditis. Prompt initiation of renal replacement therapy with close monitoring led to a successful management outcome. This case report highlights the importance of early recognition, appropriate interventions, and a multidisciplinary approach in treating uremic pericarditis.

Keywords: End-stage renal disease, uremic pericarditis, dialysis-associated pericarditis, pericardial friction rub