Average volume-assured pressure support
Average volume-assured pressure support (AVAPS) is a relatively new mode of noninvasive
positive pressure ventilation (NiPPV); only a few studies have been done to
compare its effectiveness and safety to bilevel positive airway pressure (BiPAP) in chronic
respiratory failure secondary to obesity hypoventilation syndrome, obstructive sleep apnea,
chronic obstructive pulmonary disease, and neuromuscular disorders with respiratory muscle
weakness. Only six studies were found in PubMed, and these studies had many limitations,
especially small sample sizes. This review provides detailed summaries of these studies.
These devices require more investigation.
Johnson KG. Treatment of sleep disordered breathing with
positive airway pressure devices: technology update. Med
Devices (Auckl) 2015 Oct 23;8:425–37.
Ambrogio C. Sleep and non-invasive ventilation in patients
with chronic respiratory insufficiency. Intensive Care Med
Storre JH. Average volume-assured pressure support in obesity
hypoventilation: A randomized crossover trial. Chest
Crisafulli E. Subjective sleep quality during average volume
assured pressure support (AVAPS) ventilation in patients with
hypercapnic COPD: A physiological pilot study. Lung 2009
Murphy PB. Volume targeted versus pressure support non-invasive
ventilation in patients with super obesity and chronic
respiratory failure: a randomized controlled trial. Thorax
Briones Claudett KH, et al. Noninvasive mechanical ventilation
with AVAPS in patients with COPD and hypercapnic
encephalopathy. BMC Pulm Med 2013 Mar 12;13:12. doi:
Piesiak P. Efficacy of noninvasive volume targeted ventilation
in patients with chronic respiratory failure due to kyphoscoliosis.
Adv Exp Med Biol 2015;838:53–8.
All articles are published under the Creative Commons Attribution-Non-Commercial License https://creativecommons.org/licenses/by-sa/2.0/