Vancomycin and linear IgA bullous dermatosis
Abstract
Vancomycin is a broad-spectrum antibiotic that is considered an optimal parenteral
treatment for many infections, including septicemia, pneumonia, cellulitis, endocarditis, and
meningitis caused by methicillin-resistant Staphylococcus aureus. It is the first-line treatment
for the increasing health care-associated infection Clostridium difficile pseudomembranous
colitis. More side effects are being reported secondary to increased vancomycin use. Of those
side effects, skin reactions are becoming more recognized by physicians.
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References
VISA/VRSA–Vancomycin–Intermediate/Resistant Staphylococcus
aureus fact sheet. Available at: http://www.cdc.gov/
ncidod/hip/ARESIST/visa.htm.
Korman TM, Turnidge JD, Grayson ML. Risk factors for
adverse cutaneous reactions associated with intravenous vancomycin.
J Antimicrob Chemother 1997;39:315–318.
Jones DH. Early diagnosis is key in vancomycin-induced linear
IgA bullous dermatosis and Stevens-Johnson syndrome. J
Am Osteopath Assoc 2004 Apr; 104(4):157–63.
Fortuna G, Marinkovich MP. Linear immunoglobulin A bullous
dermatosis. Clin Dermatol 2012;30:38.
Minhas JS, Immune-mediated reactions to vancomycin: A
systematic case review and analysis. Ann Allergy Asthma
Immunol 2016 Jun 4; 116(6):544–53.
Lings K, Bygum A. Linear IgA bullous dermatosis: a retrospective
study of 23 patients in Denmark. Acta Derm Venereol
;95:466–471.
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