Comparing the asthma control in overweight/obese and normal weight pediatric patients: A retrospective study in West Texas

  • Jason Huang
  • Jarrett Lever
  • Bhargavi Kola
Keywords: childhood asthma, childhood obesity, childhood overweight, asthma management


Asthma is one of the most common chronic diseases in children. Excess weight is thought to contribute adversely to this disease and has been associated with both an increased incidence and severity of asthma in multiple studies. However, this information does not seem to be conclusive, since there are also studies showing either no relationship or a relationship only in certain subpopulations of children. The aim of this study was to see if we could identify any pattern in the relationship of weight and asthma severity and control in our pediatric population at a university affiliated clinic in rural West Texas. We were unable to find statistically significant differences either in the overall population or in the boys or girls subpopulations. We estimate based on our results that future studies would need at least 800 children to achieve adequate statistical power. More well designed studies are needed to clarify and confirm the relationship between obesity and asthma control and severity in children.


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Zahran HS, Bailey CM, Damon SA, et al. Vital Signs:

Asthma in Children—United States, 2001-2016. MMWR

Morb Mortal Wkly Rep 2018;67:149–55.

Beuther DA, Weiss ST, Sutherland ER. Obesity and asthma.

Am J Respir Crit Care Med 2006;174:112–9.

Lazarus R, Colditz G, Berkey CS, et al. Effects of body fat on

ventilatory function in children and adolescents: cross-sectional

findings from a random population sample of school

children. Pediatr Pulmonol 1997;24:187–94.

Gennuso J, Epstein LH, Paluch RA, et al. The relationship

between asthma and obesity in urban minority children and

adolescents. Arch Pediatr Adolesc Med 1998;152:1197–200.

Manion AB. Asthma and obesity: the dose effect. Nurs Clin

North Am 2013;48:151–8.

Beuther DA, Sutherland ER. Overweight, obesity, and incident

asthma: a meta-analysis of prospective epidemiologic

studies. Am J Respir Crit Care Med 2007;175:661–6.

Stenius-Aarniala B, Poussa T, Kvarnström J, et al. Immediate

and long term effects of weight reduction in obese

people with asthma: randomised controlled study. BMJ


Eneli IU, Skybo T, Camargo CA. Weight loss and asthma: a

systematic review. Thorax 2008;63:671–6.

Ekström S, Hallberg J, Kull I, et al. Body mass index status

and peripheral airway obstruction in school-age children: a

population-based cohort study. Thorax 2018; 73(6):538–545.

Center for Disease Control and Prevention. Asthma and

Obesity. 2013. (Accessed June 1, 2018, at https://www.cdc.


Lavoie KL, Bacon SL, Labrecque M,et al. Higher BMI is

associated with worse asthma control and quality of life but

not asthma severity. Respir Med 2006;100:648–57.

Program NAEaP. Expert Panel Report 3 (EPR-3): Guidelines

for the Diagnosis and Management of Asthma-Summary

Report 2007. J Allergy Clin Immunol 2007;120:S94–138.

Akinbami LJ, Rossen LM, Fakhouri THI, et al. Asthma

prevalence trends by weight status among US children aged

–19 years, 1988-2014. Pediatr Obes 2017.

Toennesen LL, Bjerregaard A, Porsbjerg C, et al. Overweight

in childhood and adolescence: Does it lead to airway hyperresponsiveness

in adulthood? J Asthma 2018;55:137–44.

Kattan M, Kumar R, Bloomberg GR, et al. Asthma control,

adiposity, and adipokines among inner-city adolescents.

J Allergy Clin Immunol 2010;125:584–92.

Borrell LN, Nguyen EA, Roth LA, et al. Childhood obesity

and asthma control in the GALA II and SAGE II studies. Am

J Respir Crit Care Med 2013;187:697–702.

Peters-Golden M, Swern A, Bird SS, et al. Influence of body

mass index on the response to asthma controller agents. Eur

Respir J 2006;27:495–503.

Boulet LP, Franssen E. Influence of obesity on response to

fluticasone with or without salmeterol in moderate asthma.

Respir Med 2007;101:2240–7.

Forno E, Lescher R, Strunk R, et al. Decreased response to

inhaled steroids in overweight and obese asthmatic children.

J Allergy Clin Immunol 2011;127:741–9.

How to Cite
Huang, J., Lever, J., & Kola, B. (2018). Comparing the asthma control in overweight/obese and normal weight pediatric patients: A retrospective study in West Texas. The Southwest Respiratory and Critical Care Chronicles, 6(25), 14-18.