Pneumomediastinum secondary to invasive and non-invasive mechanical ventilation

  • Sara Mousa
  • Hawa Edriss

Abstract

Pneumomediastinum (PM) is defined as the presence of abnormal gas in the mediastinum. It is a known complication of invasive mechanical ventilation and has been reported with non-invasive ventilation. Recent studies have reported that the incidence of barotrauma is lowest in post-operative patients and is highest in mechanically ventilated patients with acute respiratory distress syndrome. The incidence has dropped with the low tidal volume ventilation technique. Chest x-rays can miss up to 25% of small PMs detected by computed tomography scans of the chest. Pneumomediastinum is managed with low tidal volume ventilation with plateau pressures <30 cm H2O and treatment of the underlying lung disease. Novel ways of ventilation, such as high frequency oscillatory ventilation and asynchronous independent lung ventilation, may improve ventilation in some patients.

Keywords: Pneumomediastinum, barotrauma, mechanical ventilation, air leak, ventilator induced lung injury

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References

Gasser CR, Pellaton R, Rochat CP. Pediatric spontaneous

pneumomediastinum: narrative literature review. Pediatric

Emergency Care 33(5):370–374.

Hoo GW. Barotrauma and mechanical ventilation. emedicine.

medscape.com/article/296625-overview. Updated: Apr 18, 2018.

Caceres M, Braud R L, Maekawa R, et al. Secondary pneumomediastinum:

A retrospective comparative analysis. Lung

Sep-Oct;187(5):341–6.

De Latorre FJ, Klamburg J J, Leon C, et al. Incidence of

pneumothorax and pneumomediastinum in patients with aspiration

pneumonia requiring ventilatory support. Chest 1977

Aug;72(2):141–4.

Pérez LA, González DM, Álvarez KM, et al. Nasal CPAP

versus mechanical ventilation in 28 to 32-week preterm

infants with early surfactant administration. Biomedica 2014

Oct-Dec;34(4):612–23.

Loza RC, Rodríguez GV, Fernández NM. Ventilator-induced

lung injury (VILI) in acute respiratory distress syndrome:

volutrauma and molecular effects. Open Respir Med J 2015

Jun 26;9:112–9.

Weng L, Huang X, Chen L, et al. Prognostic factors for

severe Pneumocystis jiroveci pneumonia of non-HIV patients

in intensive care unit: a bicentric retrospective study. BMC

Infect Dis. 2016;16(1):528.

Turlapati KM, Spear RM, Paterson BM. Mediastinal tube

placement in children with pneumomediastinum: hemodynamic

changes and description of technique. Crit Care Med

Jul;24(7):1257–60.

Boudreault F, Pinilla-Vera M, Englert JA, et al. Zinc deficiency

primes the lung for ventilator-induced injury. JCI Insight 2017

Jun 2;2(11). pii: 86507. doi: 10.1172/jci.insight.86507.

Okada M, Adachi H, Shibuya Y, et al. Diagnosis and treatment

of patients with spontaneous pneumomediastinum.

Respir Investig 2014 Jan. 52(1):36–40.

Wong KS, Wu HM, Lai SH, et al. Spontaneous pneumomediastinum:

analysis of 87 pediatric patients. Pediatr Emerg

Care 2013 Sep. 29(9):988–91.

Wu CH, Chen CM, Chen CC, et al. Esophagography after

pneumomediastinum without CT findings of esophageal perforation:

is it necessary?. AJR Am J Roentgenol 2013 Nov.

(5):977–84.

Ho AS, Ahmed A, Huang JS, et al. Multidetector computed

tomography of spontaneous versus secondary pneumomediastinum

in 89 patients: can multidetector computed tomography

be used to reliably distinguish between the 2 entities?.

J Thorac Imaging 2012 Mar. 27(2):85–92.

Umegaki T, Kenichiro S, Akihisa N, et al. Impact of steroid medication

before hospital admission on barotrauma in mechanically

ventilated patients with acute respiratory distress syndrome

in intensive care units. J Anesth 2014 Oct;28(5):681–6.

Yang L, Li F, Li D, et al. Clinical analysis of complications after

non- invasive positive pressure ventilation and an inquiry

into the respiratory treatment strategy in patients with SARS.

Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2004 May;16(5):

–3.

Zhang L, Shen M, Zhang F, et al. Survival analysis and

risk factors for mortality in connective tissue diseaseassociated

pneumomediastinum. Rheumatol Int 2014 Dec;

(12):1657–63.

Colombi D, Ehlers-Tenenbaum S, Palmowski K, et al.

Spontaneous pneumomediastinum as a potential predictor

of mortality in patients with idiopathic pulmonary fibrosis.

Respiration 2016;92(1):25–33.

Ebina M, Inoue A, Takaba A. Management of spontaneous

pneumomediastinum: Are hospitalization and prophylactic

antibiotics needed? Am J Emerg Med 2017 Aug;35(8):

–1153.

García LG, Corsino Rey, Medina A, et al. Severe subcutaneous

emphysema and pneumomediastinum secondary to

noninvasive ventilation support in status asthmaticus. Indian

J Crit Care Med 2016 Apr;20(4):242–4.

Bakhshaee M, Jokar MH, Mirfeizi Z, et al. Subcutaneous

emphysema, pneumomediastinum and pneumothorax in a

patient with dermatomyositis. Iran J Otorhinolaryngol 2017

Mar; 29(91):113–116.

Ruggeri P, Girbino G. Fatal pneumomediastinum associated

with use of noninvasive mechanical ventilation. Respirol

Case Rep 2014 Dec;2(4):126–8.

Weaver JB, Kumar AB. Tension pneumomediastinum: rare

cause of acute intraoperative circulatory collapse in the setting

of unremarkable TEE finding. J Clin Anesth 2017 Feb;

:136–138.

Colin GC, Ghaye B, Coche E Tension pneumomediastinum

secondary to thoracic air-leak syndrome in chronic graft versus

host disease. Diagn Interv Imaging 2014 Mar;95(3):317–9.

McGinley J, Corcoran T, Canny G, et al. A case of pneumomediastinum

in paediatric ARDS: to oscillate or not? Paediatr

Anaesth 2001 May;11(3):366–9.

Mehdiratta N, Archer M, Stewart M, et al. Novel airway and

ventilator management of tracheobronchial disruption after

blunt trauma. Ann Thorac Surg 2017 Nov;104(5):e359–e361.

Ali HS, Hassan IF, George S. Extra corporeal membrane oxygenation

to facilitate lung protective ventilation and prevent

ventilator-induced lung injury in severe Pneumocystis pneumonia

with pneumomediastinum: a case report and short literature

review. BMC Pulm Med 2016 Apr 14;16(1):52. doi:

1186/s12890-016-0214-4.

Paluszkiewicz P, Bartosinski J, Rajewska-Durda K, et al. Cardiac

arrest caused by tension pneumomediastinum in a Boerhaave

syndrome patient. Ann Thorac Surg 2009 Apr;87(4):

–8.

Published
2019-01-18
How to Cite
Mousa, S., & Edriss, H. (2019). Pneumomediastinum secondary to invasive and non-invasive mechanical ventilation. The Southwest Respiratory and Critical Care Chronicles, 7(27), 36-42. https://doi.org/10.12746/swrccc.v7i27.524