Magnesium Infusion for Refractory Non-surgical Pheochromocytoma Crisis

  • Chelsea Kristin Krueger University of Texas MD Anderson Cancer Center Division of Pharmacy, Texas Tech University Health Sciences Center School of Pharmacy http://orcid.org/0000-0003-2378-1981
  • Kimberly A Turner University of Texas MD Anderson Cancer Center Department of Critical Care
  • Raymond A Moreno University of Texas MD Anderson Cancer Center Department of Critical Care
  • Biosha B Jones University of Texas MD Anderson Cancer Center Department of Critical Care
  • Olakunle Idowu University of Texas MD Anderson Cancer Center Department of Critical Care
Keywords: Pheochromocytoma, magnesium sulfate, hypertension, hemodynamics, adrenal gland neoplasm

Abstract

Pheochromocytoma crisis is a rare medical emergency characterized by severe hypertension, shock, and multiorgan failure. Despite its widespread availability, low cost and wide therapeutic index, magnesium sulfate has primarily been utilized as an adrenergic antagonist during pheochromocytoma resection. This case report describes a 57-year-old male with recurrent nonsurgical pheochromocytoma and crisis refractory to adrenergic antagonism. Initiation of magnesium sulfate continuous infusion provided rapid hemodynamic control in the setting of inoperable disease. This case highlights the role and dosing of magnesium sulfate in the management of pheochromocytoma crisis.

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Published
2019-07-19
How to Cite
Krueger, C. K., Turner, K. A., Moreno, R. A., Jones, B. B., & Idowu, O. (2019). Magnesium Infusion for Refractory Non-surgical Pheochromocytoma Crisis. The Southwest Respiratory and Critical Care Chronicles, 7(30), 47-50. https://doi.org/10.12746/swrccc.v7i30.531