A case report of an immunocompetent patient with Coccidioides meningoencephalitis with atypical brain magnetic resonance imaging findings during a 1 year follow-up

  • Dongkwan Jin
  • Juliana Gomez

Abstract

Coccidioides meningoencephalitis is a central nervous system (CNS) fungal infection with Coccidioides species which can lead to various CNS complications, such as hydrocephalus, vasculitis, and stroke. Most cases reported with Coccidioides meningoencephalitis were in immunocompromised patients, and the radiologic characteristics on this condition are not well established. Here we report a case of Coccidioides meningoencephalitis in an immunocompetent patient with one-year follow-up brain magnetic resonance image (MRI) studies after successful treatment with antifungal drugs. The MRI demonstrated subcortical parenchymal lesions, selectively involving the white matter, and persistent meningeal enhancement.

Keywords: Coccidioides, Coccidioidomycosis, meningoencephalitis, immunocompetent, MRI

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References

Murthy JM, Sundaram C. Fungal infections of the central

nervous system. Handb Clin Neurol 2014;121:1383–1401.

Galgiani JN, Ampel NM, Blair JE, et al. Coccidioidomycosis.

Clin Infect Dis 2005;41(9):1217–1223.

Johnson RH, Einstein HE. Coccidioidal meningitis. Clin

Infect Dis 2006;42(1):103–107.

Kleinschmidt-DeMasters BK, Mazowiecki M, et al. Coccidioidomycosis

meningitis with massive dural and cerebral

venous thrombosis and tissue arthroconidia. Arch Pathol Lab

Med 2000;124(2):310–314.

Dewsnup DH, Galgiani JN, Graybill JR, et al. Is it ever safe to

stop azole therapy for Coccidioides immitis meningitis? Ann

Intern Med 1996;124(3):305–310.

Published
2019-04-19
How to Cite
Jin, D., & Gomez, J. (2019). A case report of an immunocompetent patient with Coccidioides meningoencephalitis with atypical brain magnetic resonance imaging findings during a 1 year follow-up. The Southwest Respiratory and Critical Care Chronicles, 7(28), 33-37. https://doi.org/10.12746/swrccc.v7i28.542