TY - JOUR AU - Kenneth Iwuji AU - Sharan Bijlani AU - Rose Izuchi AU - David Sotello PY - 2018/04/18 Y2 - 2024/03/28 TI - Autoimmunity in cystic fibrosis: significance and clinical implications JF - The Southwest Respiratory and Critical Care Chronicles JA - The Chronicles VL - 6 IS - 23 SE - In The Clinic DO - 10.12746/swrccc.v6i23.470 UR - https://pulmonarychronicles.com/index.php/pulmonarychronicles/article/view/470 AB - Anti-neutrophil cytoplasmic antibodies specific for bactericidal/permeability-increasing protein (BPI-ANCA) are frequently present in cystic fibrosis patients. These autoantibodies are believed to develop in response to infection and colonization by Pseudomonas aeruginosa. Development of BPI-ANCA has been shown to correlate with the severity of lung infection and poor prognosis in cystic fibrosis patients. ER -