Kcentra® (Prothrombin Complex Concentrate [Human]): Its indications, side effects, and contraindications

  • Amr Ismail Department of Internal Medicine at Texas Tech University Health Sciences Center, Lubbock, Texas
Keywords: Kcentra, four factor prothrombin complex concentrate, acute major bleeding, urgent hemostasis, INR reversal, warfarin

Abstract

Patients with a high risk for thromboembolic events can be on long-term warfarin. These
patients need close monitoring of their INR and for signs of bleeding. Conventionally, fresh
frozen plasma (FFP) is used for reversal of INR in patients with major bleeding or who need
urgent surgery or invasive procedures. Kcentra is now available as an alternative to FFP for
rapid reversal of INR and urgent hemostasis.

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Published
2017-10-16
How to Cite
Ismail, A. (2017). Kcentra® (Prothrombin Complex Concentrate [Human]): Its indications, side effects, and contraindications. The Southwest Respiratory and Critical Care Chronicles, 5(21), 11-15. https://doi.org/10.12746/swrccc.v5i21.423