Kcentra® (Prothrombin Complex Concentrate [Human]): Its indications, side effects, and contraindications
Patients with a high risk for thromboembolic events can be on long-term warfarin. These
patients need close monitoring of their INR and for signs of bleeding. Conventionally, fresh
frozen plasma (FFP) is used for reversal of INR in patients with major bleeding or who need
urgent surgery or invasive procedures. Kcentra is now available as an alternative to FFP for
rapid reversal of INR and urgent hemostasis.
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