Novel origin of cerebral phaeohyphomycosis: A case report

  • Christopher Daniele
  • Miriam Ferguson
  • Cooper Phillips
  • Jinesh Lachmansingh
  • Jacob Nichols
  • John Fisher
  • Brady Holstead
  • Akwasi Opoku


Cerebral phaeohyphomycosis is infection of the central nervous system (CNS) caused by dematiaceous fungi. The most common mechanisms of infection are by direct extension from the paranasal sinuses or by hematogenous spread. The mortality rate is high and ranges from 50%–79% in the limited studies on this infection. Our case describes a young man without any preexisting disease who acquired cerebral phaeohyphomycosis following nasal inhalation of garden mushrooms. Despite aggressive treatment, he ultimately died due to this severe infection. Our case report discusses our treatment approach and reviews the literature on this deadly infection.

Keywords: fungal infection, cerebral abscess, Bipolaris, phaeohyphomycosis


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How to Cite
Daniele, C., Ferguson, M., Phillips, C., Lachmansingh, J., Nichols, J., Fisher, J., Holstead, B., & Opoku, A. (2020). Novel origin of cerebral phaeohyphomycosis: A case report. The Southwest Respiratory and Critical Care Chronicles, 8(33), 52-55.